Defects in AMPAR trafficking and microglia activation underlie socio-cognitive deficits associated to decreased expression of Phosphodiesterase 2A
Sébastien Delhaye, Marielle Jarjat, Asma Boulksibat…·Barbara Bardoni
This study investigates the role of PDE2A in socio-cognitive deficits by analyzing Pde2a+/- mice, revealing microglia activation and AMPAR trafficking defects linked to cognitive impairments.