Zdeněk Dvořák

This study identifies Sutterella sp. as a commensal pathobiont that inhibits IL-22 production and AhR activity, offering insights into gut inflammation regulation.

This study evaluates FKK6, a microbial mimic of an indole metabolite, as a therapy for colitis-associated colorectal cancer in mice, showing anti-tumor effects and safety.

This paper performs in vitro pharmacological profiling of FKK6, showing high PXR selectivity, intestinal permeability, and rapid metabolism, supporting its potential preclinical development.