Yohannes Tesfaigzi

The paper establishes a framework for designing splicing experiments in deep 3'-biased single-cell RNA sequencing by analyzing depth requirements and benchmarking against bulk RNA sequencing.

This paper introduces a high-throughput mucus microrheology platform using Differential Dynamic Microscopy to quantify mucus properties across various conditions and applications.

The paper evaluates splicing models, identifies performance gaps, and introduces a cell-type-specific model for improved splice site prediction in human airway epithelial cells.

This paper introduces a drug-free nasal spray that captures and neutralizes respiratory pathogens, showing high efficacy in mice against influenza.

This study identifies eight novel genetic signals associated with asthma-COPD overlap through a genome-wide association analysis involving multiple cohorts.

This study expands the genetic landscape of COPD by identifying 82 risk loci, revealing associations with lung function, cell types, and comorbidities.