Author

Jeffrey J. Wine

Stanford MedicineORCID 0000-0002-4038-1392Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Carlos E. MillaiD· 2 shared Dawn T. BravoiD· 2 shared Jayakar V. NayakiD· 2 shared Zachary M. SellersiD· 2 shared Ameen A. Salahudeen· 1 shared Arpit Batish· 1 shared Calvin J. Kuo· 1 shared Ciaran M. LeeiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersBioengineering

Carlos E. MillaORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintJan 24, 2025

Durable reconstitution of sinonasal epithelium by transplant of CFTR gene corrected airway stem cells

Dawn T. Bravo, Sriram Vaidyanathan, Jeanette B Baker…·Jayakar V. Nayak

This study demonstrates that gene-corrected human airway stem cells can durably engraft and restore CFTR function in murine respiratory epithelium, offering a potential therapy for cystic fibrosis.

DOI 10.1101/2025.01.24.634776

mousehuman

𝕏 PostBluesky

BioengineeringbioRxivPreprintFeb 26, 2019

Highly Efficient Repair of the ΔF508 Mutation in Airway Stem Cells of Cystic Fibrosis Patients with Functional Rescue of the Differentiated Epithelia

Sriram Vaidyanathan, Ameen A. Salahudeen, Zachary M. Sellers…·Matthew H. Porteus

This paper corrects the ΔF508 mutation in CF patient airway stem cells using CRISPR-Cas9 and AAV6, achieving high correction rates and functional rescue in differentiated epithelia.

DOI 10.1101/561183

humangenetic perturbation / CRISPR

𝕏 PostBluesky