Author

Jayakar V. Nayak

Stanford MedicineORCID 0000-0003-4454-0861Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Carlos E. MillaiD· 2 shared Dawn T. BravoiD· 2 shared Jeffrey J. WineiD· 2 shared Zachary M. SellersiD· 2 shared Alexandar TzankoviD· 1 shared Ameen A. Salahudeen· 1 shared Andrew Z Ma· 1 shared Arpit Batish· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersBioengineering

Carlos E. MillaORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 9, 2026

Coordinated immune-epithelial dynamics in the nasal epithelium protect against respiratory virus infection

Yao Yu Yeo, Hsin‐Yi Chen, Bokai Zhu…·Sizun Jiang

The paper identifies IL13-driven immune-epithelial remodeling in the nasal epithelium that restricts respiratory virus infection by reshaping the mucus barrier.

DOI 10.64898/2026.06.08.726938

humanspatial transcriptomics

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BioengineeringbioRxivPreprintJan 24, 2025

Durable reconstitution of sinonasal epithelium by transplant of CFTR gene corrected airway stem cells

Dawn T. Bravo, Sriram Vaidyanathan, Jeanette B Baker…·Jayakar V. Nayak

This study demonstrates that gene-corrected human airway stem cells can durably engraft and restore CFTR function in murine respiratory epithelium, offering a potential therapy for cystic fibrosis.

DOI 10.1101/2025.01.24.634776

mousehuman

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BioengineeringbioRxivPreprintFeb 26, 2019

Highly Efficient Repair of the ΔF508 Mutation in Airway Stem Cells of Cystic Fibrosis Patients with Functional Rescue of the Differentiated Epithelia

Sriram Vaidyanathan, Ameen A. Salahudeen, Zachary M. Sellers…·Matthew H. Porteus

This paper corrects the ΔF508 mutation in CF patient airway stem cells using CRISPR-Cas9 and AAV6, achieving high correction rates and functional rescue in differentiated epithelia.

DOI 10.1101/561183

humangenetic perturbation / CRISPR

𝕏 PostBluesky