Diana Nakib

The paper integrates multiple datasets to create a comprehensive human liver cell atlas, identifying new cell types and associations with demographic factors.

This paper uses Visium HD spatial transcriptomics to create a high-resolution map of human liver cell types and spatial gene expression in adult and pediatric samples.

This study identifies RUNX1 as a key transcriptional regulator of fibrogenic and inflammatory signaling in cholangiocytes, showing its inhibition reduces biliary fibrosis and inflammation in models of cholangiopathy.

The paper constructs a single-cell RNA-seq atlas of the human pediatric liver and identifies age-related gene signatures that differ from adult livers and are relevant to pediatric liver diseases.