Eija Jokitalo

The paper shows filopodia can penetrate neighboring cells to form impact sites that initiate trans-endocytosis, with internalized tips often being double-membraned and associated with endoplasmic reticulum.

The paper develops a protocol to characterize epileptogenic tissue using multimodal data from surgical samples, aiming to improve diagnosis and treatment of drug-resistant epilepsy.

This study shows that Sac1 regulates Golgi V-ATPase assembly by controlling TGN membrane composition through lipid exchange, leading to Golgi fragmentation and impaired glycosylation.

This study shows that dispersal behavior, not morphology, drives social polymorphism in Formica ants, suggesting a 'behavior first' evolutionary mechanism.

This study identifies RRBP1 as a novel peroxisome biogenesis factor in human cells, showing it promotes peroxisome formation and stabilizes peroxisomal proteins.

This study shows mitochondrial dysfunction in astrocytes disrupts primary ciliary homeostasis, linking mitochondrial stress to ciliary signaling and neurodegenerative disease mechanisms.

This study generates and benchmarks functionally mature stem cell-derived islets, showing they closely resemble primary adult islets in transcriptional and functional properties.

DeepACSON segments myelinated axons, cell nuclei, and mitochondria in low-resolution 3D-EM datasets of rat brain tissue, capturing morphological changes post-injury.

The paper develops an automated 3D segmentation pipeline for axonal morphology analysis in rat white matter and finds reduced axonal diameter in chronic brain injury.