Author

Saeed Siri

University of Notre DameORCID 0000-0002-4185-0680Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Approach:simulation· 1

Frequent Co-Authors

Alice A. BurchettiD· 2 shared Meenal DattaiD· 2 shared Jun LiiD· 1 shared Xin LüiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersImmunology

Alice A. BurchettORCID

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2 papers

Recent·Most cited

ImmunologyCellular and Molecular BioengineeringPeer-reviewedOct 1, 2024

Novel 3-D macrophage spheroid model reveals reciprocal regulation of immunomechanical stress and mechano-immunological response

Alice A. Burchett, Saeed Siri, Jun Li…·Meenal Datta

This study shows macrophages generate mechanical stress in agarose gels and respond to environmental stiffness and cytokine signals.

14 citations

mousebulk RNA-seq

𝕏 PostBluesky

BiophysicsBiomechanics and Modeling in MechanobiologyPeer-reviewedSep 19, 2024

Simulating the Impact of Tumor Mechanical Forces on Glymphatic Networks in the Brain Parenchyma

Saeed Siri, Alice A. Burchett, Meenal Datta

This study simulates how brain tumor mechanical forces affect glymphatic transport in the brain parenchyma, showing increased stress and strain reduce CSF flow rates.

15 citations

humansimulation

𝕏 PostBluesky