Author

Kamesh Ayasolla

Feinstein Institute for Medical ResearchORCID 0000-0002-4265-2168Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Insha ZahooriD· 2 shared Mena Fatma· 2 shared Mir SajadiD· 2 shared Mohammad Ejaz Ahmed· 2 shared Mohammad NematullahiD· 2 shared Ramandeep RattaniD· 2 shared Shailendra GiriiD· 2 shared Ashwani Malhotra· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersImmunology

Insha ZahoorORCID

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4 papers

Recent·Most cited

ImmunologyProceedings of the National Academy of SciencesPeer-reviewedAug 4, 2025

Immuno-Responsive Gene-1: The Mitochondrial Key to Th17 Cell Pathogenicity in CNS Autoimmunity

Mohammad Nematullah, Mena Fatma, Guoli Zhou…·Shailendra Giri

This study identifies Irg1 as a protective gene that negatively regulates pathogenic Th17 cells in CNS autoimmunity using knockout mice and single-cell RNA sequencing.

2 citations

mousebulk RNA-seq

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ImmunologybioRxivPreprintSep 25, 2023

Maresin-1 promotes neuroprotection and prevents disease progression in experimental models of multiple sclerosis through metabolic reprogramming and shaping innate and adaptive disease-associated cell types

Insha Zahoor, Mohammad Nematullah, Mohammad Ejaz Ahmed…·Shailendra Giri

This study shows that MaR1 treatment reduces inflammation, protects neurons, and improves metabolism in a mouse model of multiple sclerosis.

2 citations

mouseexperimental assay

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Developmental BiologyFrontiers in Cardiovascular MedicinePeer-reviewedMay 31, 2021

Extracellular Superoxide Dismutase (EC-SOD) Regulates Gene Methylation and Cardiac Fibrosis During Chronic Hypoxic Stress.

Ayan Rajgarhia, Kamesh Ayasolla, Nahla Zaghloul…·Mohamed Ahmed

This study shows that EC-SOD overexpression reduces cardiac fibrosis and RASSF1A methylation in hypoxic mice.

21 citations

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintFeb 4, 2018

Apolipoprotein L1 Dynamics in Human Parietal Epithelial Cell Molecular Phenotype Kinetics

Vinod Kumar, Himanshu Vashistha, Xiqian Lan…·Pravin C. Singhal

The paper investigates the role of APOL1 in PEC phenotype transitions and its interaction with miR193a, showing a feedback loop and its modulation by HIV, IFN-y, and VDA.

DOI 10.1101/259267

humanbulk RNA-seq

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