Jonathon D. Walsh

This paper uses a C. elegans model to functionally classify an ADPKD variant, showing it acts recessively by disrupting polycystin complex function.

This study shows that the ECM gene mec-9 affects sensory cilia function and EV shedding in C. elegans through non-autonomous mechanisms.

The paper identifies cargo proteins associated with polycystin EVs in C. elegans using a modular proximity labeling approach, revealing their role in EV subtype specificity.

The paper identifies genes that regulate microtubule glutamylation and ciliary integrity in C. elegans, showing their role in preventing neuronal ciliary degeneration.