Zachary J. Rogers

This paper develops a nanoparticle-based method to deliver Cre mRNA for lung adenocarcinoma modeling in mice, avoiding immune activation and enabling accurate tumor-immune dynamics studies.

This study identifies lymph node resident memory T cells (LNRM) as a distinct subset with unique effector capabilities compared to lung resident memory T cells and central memory T cells.

This study shows PD-1 blockade during T cell priming promotes an intermediate-exhausted CD8 T cell state that supports durable anti-tumor immunity after surgery and metastatic challenge, better than effector or memory-like T cells.