Amy J. Wisdom

The paper identifies cross-presented tumor antigens in glioblastoma and shows that targeting these antigens with mRNA vaccines improves anti-tumor immunity.

The paper compares radiation response in autochthonous and transplant sarcomas in mice with and without adaptive immunity, finding higher cure rates in transplant tumors with immune function.

This study shows that loss of Atrx in a mouse sarcoma model activates the ALT telomere maintenance pathway independently of telomerase, leading to telomere instability and APB formation.

This study shows that combining radiotherapy with CpG, a TLR9 agonist, enhances tumor response in a mouse sarcoma model by boosting CD8 T cell activity.