David M Sachs

The paper introduces HIV SMRTcap, a method for characterizing HIV-1 reservoirs by identifying integration sites and proviral integrity using long-read sequencing, and validates its performance across subtypes and tissue samples.

This study identifies a Netrin-1 signaling pathway that regulates muscle stem cell protrusion dynamics and quiescence maintenance through cytoskeletal components.

The paper develops a robotic system for precise cell seeding in microfluidic chips to improve the repeatability and physiological relevance of tube-shaped organoids.

The paper describes the development of a custom robotic system for automated data collection and stimulation of microfluidic organoid chips.