Duane A. Compton

This study shows that developmental regulation of kinetochore phosphorylation, specifically HEC1 hypophosphorylation in hPSCs, leads to reduced mitotic fidelity, which is improved by differentiation.

This study shows Cyclin A2 and B1/B2 have opposing roles in regulating kinetochore dynamics and mitotic progression in human cells.

This study shows Cyclin A/Cdk1 promotes chromosome alignment and timely mitotic progression by regulating kinetochore protein localization and correcting erroneous microtubule attachments.