Author

Samantha Eccles

The University of MelbourneORCID 0000-0002-4446-083XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Assay:structural biology· 1

Frequent Co-Authors

Hannah Kate VanyaiiD· 2 shared Marnie E. BlewittiD· 2 shared Alexandra D. GurzauiD· 1 shared Andrew J KuehiD· 1 shared Andrew Keniry· 1 shared Andrew P. LeisiD· 1 shared Iromi Wickramasinghe· 1 shared James M. MurphyiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersDevelopmental Biology

Hannah Kate VanyaiORCID

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2 papers

Recent·Most cited

Developmental BiologybioRxivPreprintNov 12, 2026

A novel mouse model recapitulates features of the neurodevelopmental disorder 3p25.3 microdeletion syndrome

Sophie TB Morgan, Hannah K Vanyai, Marnie E Blewitt…·Andrew J Kueh

This study develops a novel mouse model for 3p25.3 microdeletion syndrome, showing it recapitulates key features and identifies Brpf1 as a contributor to congenital defects.

DOI 10.64898/2026.11.10.765518

mouseexperimental assay

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BiochemistrybioRxivPreprintFeb 5, 2026

DNA binding by ATPase-adjacent domains stimulates SMCHD1 ATPase activity

Alexandra D. Gurzau, Richard W. Birkinshaw, Andrew P. Leis…·Marnie E. Blewitt

This study identifies a second DNA-binding site in SMCHD1 and shows that DNA binding stimulates its ATPase activity, revealing a mechanism for gene silencing.

1 citation

mousestructural biology

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