Xuhua Wang

The paper introduces ALICE, a platform that uses function-guided in silico evolution to design AAV capsids with tailored properties, demonstrating improved targeting and tropism in mice.

This paper introduces FeatNN, a coevolutionary strategy for predicting compound-protein binding affinity by jointly representing protein sequence and structure information, achieving higher accuracy than existing methods.

This study uses scRNA-seq to identify immune cell-driven angiogenesis mechanisms in rat spinal cord injury.

This study develops a noninvasive nanodrug delivery system for spinal cord injury that targets both ROS scavenging and neuronal excitability, leading to significant functional recovery in rats.