Faridoddin Mirshahi

The paper investigates the effect of PNPLA3I148M on bone mass in a mouse model, finding it causes bone loss and alters bone metabolism independently of MASLD.

This study shows that loss of TIM4 in Kupffer cells impairs efferocytosis of apoptotic hepatocytes in NASH, promoting liver fibrosis, and that restoring TIM4 reduces fibrosis.

This study investigates sex differences in bone loss associated with MASLD using DIAMOND mice, identifying potential liver-secreted factors involved in bone resorption.

The paper shows that anti-tumor immunity in HCC relies on monocyte-driven tissue homeostasis rather than direct tumor cytotoxicity, highlighting the importance of restoring liver integrity.