Author
Ping Zhang
The Ohio State UniversityORCID 0000-0002-4601-0779Unclaimed ORCID profile · follow to get notified of new preprints
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Biology Disciplines
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2021-2025 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 20 mutual co-author links4 papers
Recent·Most cited
- BioinformaticsPatternsPeer-reviewed
Chemical-induced Gene Expression Ranking and its Application to Pancreatic Cancer Drug Repurposing
Thai-Hoang Pham, Yue Qiu, Jiahui Liu…·Ping Zhang
The paper introduces a deep learning framework, CIGER, for predicting gene expression rankings induced by chemicals and applies it to pancreatic cancer drug repurposing, showing improved performance over existing methods.
- BioinformaticsSociety for Industrial and Applied Mathematics eBooksPeer-reviewed
FAME: Fragment-based Conditional Molecular Generation for Phenotypic Drug Discovery
Thai-Hoang Pham, Lei Xie, Ping Zhang
FAME generates novel molecules with desired biological activity by learning from gene expression data using a conditional variational autoencoder and fragment-based generation.
- BioinformaticsNature Machine IntelligencePeer-reviewed
A deep learning framework for high-throughput mechanism-driven phenotype compound screening
Thai-Hoang Pham, Yue Qiu, Jucheng Zeng…·Ping Zhang
This paper introduces DeepCE, a deep learning framework for chemical-induced gene expression prediction and compound screening, showing improved performance over existing methods and demonstrating its application to COVID-19 drug repurposing.
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