Remigiusz Adam Serwa

This study identifies RUVBL1/2 as a host ATPase essential for rhinovirus replication and shows that its inhibition effectively blocks viral replication without resistance development.

This study shows that masitinib accumulates in lysosomes via pH-dependent trapping, disrupting autophagy by impairing lysosomal acidification.

This study shows that reduced Brg1 function in zebrafish leads to seizure-like behavior through disruption of the GABAergic system and increased neuronal activity.

The paper identifies an ALLO-1 network that coordinates mitochondrial quality control in C. elegans muscle, enabling functional recovery despite structural damage.

This study shows that S-palmitoylation differentially affects synaptic plasticity and neuronal spiking timing, targeting specific proteins in excitatory synapses.

The paper shows that TYMS protein levels change in a biphasic manner after 5-FU treatment, driven by translation rather than transcription, and identifies SIN1 as a key regulator.

The paper tracks ribosome localization during sporulation in B. subtilis and shows peptidoglycan rearrangement is essential for ribosome packing into the forespore.

The paper investigates translational control during sporulation in Bacillus subtilis, identifying translation silencing events and showing ribosome dysfunction affects sporulation timing and efficiency.

This paper introduces a method for targeted protein degradation in bacteria using degrader peptides that exploit the ClpXP protease, demonstrating its effectiveness on the essential GroEL protein.

This study shows that floxuridine enhances proteasome function in C. elegans, improves cold survival, and activates a detoxification pathway independent of SKN-1 and the germline.

The paper identifies OMA1 protease as a key factor in resolving arrested protein import intermediates in human cells through mitochondrial membrane depolarization.