BiochemistryNucleic Acids ResearchPeer-reviewed
THUMPD2 catalyzes N2-methylation on the spliceosome catalytic center of U6 snRNA and regulates pre-mRNA splicing
Wenqing Yang, Jianyang Ge, Xiaofeng Zhang…·Ru‐Juan Liu
This study identifies THUMPD2 as the methyltransferase responsible for N2-methylation of U6 snRNA at G72, showing it regulates pre-mRNA splicing and cell proliferation.
17 citations