Stephen Adams

This paper develops a targeted radiosensitizer drug conjugate that enhances tumor control and immune responses while minimizing toxicity to normal tissues.

ColorSTEM improves multicolor electron microscopy by using metal-conjugated DAB to enhance signal and simplify imaging.

This study evolves a laccase enzyme for cell surface labeling and EM, showing it can map T cell surface changes and visualize cell features without toxic H2O2.

The paper investigates whether perineuronal nets (PNNs) stabilize synaptic circuits and engram formation through high-resolution imaging and experimental approaches.

This study shows DOPAL promotes αSynuclein accumulation and impairs proteostasis in neuronal projections, contributing to Parkinson's disease progression.

The paper demonstrates improved signal-to-noise and resolution in EFTEM elemental mapping by using lower energy-loss N4,5 edges instead of core-loss M4,5 edges for lanthanide detection.

The paper develops a genetic probe to label and image glutamatergic synaptic vesicles using 3D electron microscopy and deep learning.