Kate L. Weeks

The paper presents a proteomic dataset from rat cardiomyocytes treated with doxorubicin, identifying proteins regulated in young hearts and highlighting sex differences in cardiotoxicity.

This study identifies glycophagy dysregulation as a mechanism of diabetic heart disease and shows that Gabarapl1 gene therapy improves cardiac function in diabetic mice and human cardiac organoids.

This study shows that cardiomyocyte stiffness contributes to diastolic dysfunction in cardiometabolic disease, identified through in vitro mechanical testing of isolated cardiomyocytes from mice with diet-induced disease.

This study investigates the role of B55α in cardiac transcriptome regulation, finding sex-specific effects on cardiac fibrosis and gene expression.

The paper develops methods to detect glycophagy in cardiac cells using antibodies and fluorescent markers to measure lysosomal flux and glycogen accumulation.