Elma Z. Tchilian

This study compares antibody repertoires in pigs after infection and immunisation, finding infection drives compartmentalised, individualised responses while immunisation promotes convergent, public repertoires.

This study isolates and characterizes monoclonal antibodies against Nipah virus from an mRNA-immunized pig, showing their neutralizing activity and potential for therapeutic use.

This study compares the pathogenesis and immune responses of EAavH1N1 and IDV in pigs, finding distinct viral kinetics and immune activation profiles.

This study identifies serum protein biomarkers for porcine influenza and coronavirus infections using proteomics, showing early detection and differentiation capabilities.

This study compares antigenic profiles of post-infection antisera from pigs and ferrets against human influenza A(H1N1pdm09) viruses, finding similar reactivity but limitations in detecting antigenic drift variants.

This study compares immune responses and pathogenesis in pigs infected with two porcine respiratory coronavirus strains, finding that a more severe strain induces stronger inflammation and immune responses linked to pneumonia.

This study uses single-cell RNA sequencing and flow cytometry to analyze immunological changes in pig lungs after influenza infection or vaccination, revealing lasting effects on immune cell populations and function.