Arianne C. Richard

This study shows that TCR-ligand affinity quantitatively modulates transcriptome remodelling in vivo, affecting cell division and interferon response.

The paper shows that transient immune architecture changes during infection protect low-affinity CD8 T-cell priming from Treg inhibition, ensuring broad T-cell responses.

This study compares immune responses and pathogenesis in pigs infected with two porcine respiratory coronavirus strains, finding that a more severe strain induces stronger inflammation and immune responses linked to pneumonia.

This study uses single-cell RNA sequencing and flow cytometry to analyze immunological changes in pig lungs after influenza infection or vaccination, revealing lasting effects on immune cell populations and function.

The paper introduces a method to measure expression variability in single-cell RNA sequencing data, revealing synchronized translational machinery activity in immune cells and new patterns in CD4+ T cell differentiation.

The paper quantifies barcode swapping in single-cell RNA-seq data and develops an algorithm to remove swapped reads, reducing artifacts in droplet-based experiments.