Author

Paul Cool

Robert Jones and Agnes Hunt Orthopaedic HospitalORCID 0000-0002-4985-3085Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Paul Cool1 paper

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Adrienne Margaret FlanaganiD· 2 shared Aheed Osman· 1 shared Anna Tollit· 1 shared Anna‐Christina Strobl· 1 shared Binghao ChaiiD· 1 shared Charlotte H. HulmeiD· 1 shared Christopher D. SteeleiD· 1 shared Christopher DaviesiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersPathology

Adrienne Margaret FlanaganORCID

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3 papers

Recent·Most cited

PathologyThe Journal of Pathology Clinical ResearchPeer-reviewedFeb 24, 2026

✦ In-depth digest

Impact of tissue staining and scanner variation on the performance of pathology foundation models: a study of sarcomas and their mimics

Binghao Chai, Jianan Chen, Paul Cool…·Adrienne Margaret Flanagan

Across 14 sarcoma and mimic subtypes, six pathology foundation models beat ResNet50 but lost accuracy under multi-institutional staining; adding 121 externally stained slides narrowed the gap.

6 citationstop 1%

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BioinformaticsJournal of NeurotraumaPeer-reviewedDec 5, 2024

A comprehensive proteomic and bioinformatics analysis of human spinal cord injury plasma identifies proteins associated with the complement cascade and liver function as potential prognostic indicators of neurological outcome

Gabriel Mateus Bernardo Harrington, Paul Cool, Charlotte H. Hulme…·Karina Therese Wright

3 citations

humanproteomics

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Genetic & Genomic MedicineGenome MedicinePeer-reviewedAug 30, 2022

A Genetic Model for Central Chondrosarcoma Evolution Correlates with Patient Outcome

William C. H. Cross, Iben Lyskjær, Tom Lesluyes…·Adrienne Margaret Flanagan

The paper presents a genetic model of central chondrosarcoma using genomic and epigenomic data to identify mutations and methylation patterns associated with patient outcomes.

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humanwhole-genome sequencing

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