Giovanni Cappello

This study shows that multicellular systems coordinate force generation and invasive migration through oscillatory mechanochemical feedback in 3D matrices.

This study shows electric fields modulate keratocyte migration speed and alignment without changing turning dynamics.

This study shows that osmotic compression relaxes tissue contractility in different cell types, mediated by RhoA and myosin activity, suggesting a feedback mechanism in morphogenesis.

This study shows that epithelial cell layers confined to narrow geometries exhibit tissue-level waves that undergo a phase transition, independent of confinement length, revealing an intrinsic mechanism for supracellular distance measurement.

The paper shows that extracellular matrix detects mechanical compression in multicellular aggregates by regulating cell behavior through deformation and dehydration.