Wenju Lu

The paper characterizes hyperoxia-induced senescent lung macrophages in neonatal mice using scRNA-seq data, identifying distinct clusters with specific gene expression and metabolic features.

This study develops a CKD-PH rat model through 5/6 nephrectomy and high-salt diet, showing increased Ang II and RAAS imbalance, ACE2 downregulation, and metabolic changes linked to pulmonary hypertension.

This study investigates the role of HIF-1 in COPD progression using digoxin as an inhibitor, showing its protective effects against inflammation and EMT through the HIF-1/TGF-β1/Smad3 pathway.