Oliver Lemke

This study uses proteomics to analyze glucose-stimulated insulin secretion in rat beta cells, finding that fatty acid metabolism plays a key role in the process.

This study uses AlphaFold2 to analyze how metabolism influenced enzyme structural evolution across 400 million years by examining 11,269 enzyme structures and their metabolic reactions.

The paper quantifies yeast cell responses to varying metal ions, revealing widespread proteomic and genetic impacts and common metal responsiveness properties.

This study shows that amino acid sequences determine protein abundance by affecting conformational stability and synthesis cost, using deep learning and yeast experiments.

The paper records proteomes for non-essential gene knock-outs in yeast to uncover principles of protein expression and annotate gene function.

The paper shows yeast cells can cooperatively compensate for methionine auxotrophy by using a new homocysteine synthase, HSU1, to re-assimilate hydrogen sulfide.