Jonas Zähringer

The paper shows that FACT facilitates Ubp10 release from nucleosomes after H2B deubiquitination, revealing release as the rate-limiting step for Ubp10 turnover.

This study uses MINFLUX nanoscopy to directly visualize MCM helicase activation and replisome coupling in human cells, showing sister replisomes remain coupled at ~40 nm during S phase.

DNAsight automates AFM image analysis of chromatin organization, revealing protein-specific structural signatures and nucleosome spacing distributions.

This paper introduces Brownian DNA computing, a molecular computing framework that uses DNA origami scaffolds to implement logic gates and circuits through thermal fluctuations, enabling energy-efficient and reversible computation.