J. Brooks Crickard

This study identifies a Rad54 mutation that separates its function during homologous recombination, revealing a novel intermediate essential for stabilizing D-loop structures.

This study investigates how Rad51 and Rad54 remodel donor DNA during homology search by applying tension and torsion forces, revealing their role in controlling Rad51-ssDNA filament dynamics.

This study identifies evolutionary changes in Rad51 and Dmc1 that influence recombination outcomes by altering DNA binding properties and pathway stability.

This study investigates how Rad54 mutations affect homologous recombination outcomes, finding that reduced translocation activity increases genomic rearrangements.

This study identifies a physical interaction between Dmc1 and Mlh1-Mlh3 in yeast meiosis and shows that Dmc1 promotes crossover resolution by recruiting Mlh1-Mlh3.