Mitchell V Woodhouse

This study investigates how Rad51 and Rad54 remodel donor DNA during homology search by applying tension and torsion forces, revealing their role in controlling Rad51-ssDNA filament dynamics.

This study identifies a new role for human topoisomerase IIα in promoting chromatin condensation through a polymer-collapse phase transition, independent of its catalytic activity.

This study investigates how Rad54 mutations affect homologous recombination outcomes, finding that reduced translocation activity increases genomic rearrangements.