Anna-Sophia Egger

The paper identifies TXNIP as a regulator of amino acid uptake during cellular quiescence by mediating endocytosis of the LAT1/SLC7A5 transporter.

GEMCAT predicts metabolic changes from transcriptomics or proteomics data and validates them with metabolomics, demonstrating its utility in human cell lines and inflammatory bowel disease patients.

The paper develops an automated workflow and dual-column U(H)PLC-MRM-MS method to rapidly quantify amino acids and tryptophan metabolites in human serum and plasma, applied to a prostate cancer study to identify biomarkers.

The paper quantifies proteomic effects of aneuploidy in natural yeast isolates, finding chromosome-wide dosage compensation in the proteome but not transcriptome.

The paper records proteomes for non-essential gene knock-outs in yeast to uncover principles of protein expression and annotate gene function.

This study compares proteome coverage and extraction efficiency of different solubilization agents in proteo-metabolome analysis using SPM-LLE and direct cell lysis.

The paper introduces PICor, a tool for isotopologue correction in proteomics and metabolomics, demonstrating its importance for accurate analysis of protein modification dynamics.