Genome-guided manipulation of regulators of morphogenesis in a C. albicans strain with low virulence is not sufficient to trigger a high-virulence phenotype
Ricardo Fróis-Martins, Sarah Mertens, Van Du T. Tran…·Salomé LeibundGut‐Landmann
This study shows that altering BRG1 and CYR1 in a low-virulence C. albicans strain does not increase its virulence in vivo, suggesting complex gene networks regulate fungal pathogenicity.