Author

Harry Chown

University of ManchesterORCID 0000-0002-5331-4711Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:chromatin & epigenetic regulation· 2 Organism:fungi (other)· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Johanna L. RhodesiD· 2 shared Matthew C Fisher (17773886)iD· 2 shared Michael BromleyiD· 2 shared Brandi N. Celia-SancheziD· 1 shared Knight CgiD· 1 shared Marin T. BreweriD· 1 shared Michael J. BotteryiD· 1 shared Michelle MomanyiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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2 shared papersEvolutionary Biology

Johanna L. RhodesORCID

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2 papers

Recent·Most cited

Evolutionary BiologybioRxivPreprintApr 16, 2026

The pangenome of Aspergillus fumigatus highlights the dynamics of gene gain-loss over evolutionary timescales in a human fungal pathogen

Harry Chown, Johanna L. Rhodes, Matthew C Fisher (17773886), Michael Bromley

This paper quantifies gene gain and loss dynamics in Aspergillus fumigatus over a century using a global pangenome, revealing slow genome evolution and lineage-specific resistance mechanisms.

1 citation

fungi (other)whole-genome sequencing

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MicrobiologyNature CommunicationsPeer-reviewedDec 16, 2024

Elevated mutation rates in the multi-azole resistant Aspergillus fumigatus cladedrives rapid evolution of antifungal resistance

Michael J. Bottery, Norman van Rhijn, Harry Chown…·Michael Bromley

This study identifies a mutation rate increase in a multi-azole resistant Aspergillus fumigatus clade, linking it to rapid antifungal resistance evolution.

56 citationstop 1%

fungi (other)DNA methylation

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