Author

Brian C. Richardson

Cornell UniversityORCID 0000-0002-5434-1500Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

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Bryce A. BrownfieldiD· 1 shared J. Christopher FrommeiD· 1 shared Steve L. HalabyiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperCell Biology

Bryce A. BrownfieldORCID

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1 paper

Recent·Most cited

Cell BiologyProceedings of the National Academy of SciencesPeer-reviewedFeb 28, 2024

Sec7 regulatory domains scaffold autoinhibited and active conformations

Bryce A. Brownfield, Brian C. Richardson, Steve L. Halaby, J. Christopher Fromme

This study determines the cryoEM structure of autoinhibited Sec7 and proposes an active conformation model based on functional and structural analyses.

7 citations

cryo-EMexperimental assay

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