Richard S. Hotchkiss

This study identifies multiple pathways suppressing stress-induced chronic pain and shows low-dose IL-2 effectively resolves sensitization without relying on opioid or GABA signaling.

This study uses ELISpot to assess immunomodulatory drug effects on cytokine production in sepsis patients and healthy controls.

This study develops and optimizes a diluted whole blood ELISpot assay to assess immune function in septic patients, showing it can measure cytokine responses under various conditions.

This study uses ELISpot to track changes in innate and adaptive immunity during sepsis and shows it can detect immune therapy effects.