NeurosciencebioRxivPreprint
Cell-type targeted CRISPR/Cas9 Clock knockdown in mouse VTA dopamine neurons alter sleep, behavior, and cellular excitability
Yeon Ha Ju, Janet Yinqing Zhao, Setareh Sianati…·Lief E. Fenno
This study uses CRISPR/Cas9 to knock down Clock in mouse VTA dopamine neurons, revealing effects on sleep, behavior, and excitability linked to bipolar disorder.
DOI 10.64898/2026.06.03.730017