W. Andy Tao

This study identifies cBAF as a regulator of AR-V7 expression through chromatin-mediated transcriptional termination in CRPC.

This paper engineers a ribozyme that can aminoacylate tRNA and discriminate between cognate and non-cognate tRNAs, enabling non-canonical amino acid incorporation.

This study identifies new TGM2-catalyzed histaminylation marks on core histones in cancer cells and reveals their crosstalk with γH2AX formation in DNA damage responses.

This study shows that PBRM1 in PBAF is essential for EMT and metastasis in breast cancer by enabling promoter targeting and DNA accessibility for TGFβ1-inducible genes.

This study identifies NRMLncR, a myocyte-enriched lncRNA, as a regulator of myogenesis in mouse, showing it enhances differentiation through interactions with MyoD/MyoG and CELF1.

This study establishes a robust mDIA pipeline for EV proteomics, showing library-based DIA outperforms other methods and reveals IDH1 mutation effects on EV proteomes in cholangiocarcinoma.

The paper identifies D2HG and L2HG-induced O-2-hydroxyglutarylation with chiral specificity, revealing inhibitory effects on kinases MRCKA and SLK.

This study identifies differentially expressed exosomal proteins in ARDS patients that may serve as regenerative niches for lung recovery.

This study shows the nBAF complex facilitates activity-induced transcription of IEGs by regulating RNA Polymerase II elongation through its assembly and ATPase activity.