Sandra Lacas‐Gervais

This study shows that MTPAP loss causes mitochondrial RNA processing defects, leading to type I interferon signaling upregulation through mt-dsRNA accumulation.

The paper uses 3D spheroid models to show filopodia-like protrusions help breast cancer cells invade by widening basement membrane pores.

This study characterizes large extracellular vesicles containing mitochondria (EVMs) from Alzheimer's Disease cells, showing they carry pathological mitochondrial dysfunction and spread it to recipient cells.

This study shows that impairing the AMPK-ULK1 cascade in Alzheimer's disease leads to mitochondrial dysfunction and AD-related changes, which are improved by metformin treatment.

This study characterizes two atypical BAR domain-containing proteins in Toxoplasma gondii, revealing their distinct membrane-binding properties and roles in parasite trafficking.

The paper examines mitochondrial alterations in fibroblasts from Alzheimer's disease patients and links them to clinical hallmarks and cognitive decline.

The paper identifies MAFB's role in podocyte differentiation by enabling WT1 binding to specific promoters through chromatin accessibility.