Dylan S. Baker

The paper introduces an interactive Data Integrator for uniform processing and integration of bulk RNA-seq datasets from the MorPhiC program and external sources.

DIANNE enables rapid training and inference of spatial differential attributes in histology images without manual annotations, using mixup augmentation and foundation models.

The paper identifies senescent β-cell subpopulations in humans and mice that induce pathologic dysfunction through paracrine signaling and shows JAK inhibitors can reverse this effect.

The paper introduces a cloud-based platform for analyzing calcium activity in motor neurons to identify compounds that reverse disease phenotypes in amyotrophic lateral sclerosis.

This study investigates hyperexcitability in iPSC-derived neurons from Dup15q patients, identifying mechanisms like delayed action potential maturation and KCNQ2 channel disruption.

This paper defines the cellular composition of the mouse urinary bladder using single-cell profiling and spatial analysis, identifying novel cell types and fibroblast populations associated with aging.