Author

Joel Chappell

Leuven Stem Cell InstituteORCID 0000-0002-5834-4100Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Vincent PasqueiD· 3 shared Adrian JaniszewskiiD· 2 shared Lotte VanheeriD· 2 shared San Kit ToiD· 2 shared Adrien RihouxiD· 1 shared Alejandro SifrimiD· 1 shared Alison KerremansiD· 1 shared Andréa Alex SchiavoiD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersDevelopmental Biology

Vincent PasqueORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintMar 8, 2023

A multi-omics genome-and-transcriptome single-cell atlas of human preimplantation embryogenesis reveals the cellular and molecular impact of chromosome instability

Elia Fernandez Gallardo, Alejandro Sifrim, Joel Chappell…·Thierry Voet

This study uses single-cell genome-and-transcriptome sequencing to analyze the impact of chromosome instability on cellular states and development in human preimplantation embryos.

18 citations

humanscRNA-seq

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BioinformaticsbioRxivPreprintSep 23, 2020

Predicting the Key Regulators of Cell Identity in Human Adult Pancreas

Lotte Vanheer, Federica Fantuzzi, San Kit To…·Vincent Pasque

The paper reconstructs gene regulatory networks in human adult pancreatic cell types and identifies key transcription factors regulating cell identity.

4 citations

humanscRNA-seq

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Developmental BiologybioRxivFeb 9, 2019

Dynamic Erasure of Random X-Chromosome Inactivation during iPSC Reprogramming

Adrian Janiszewski, Irene Talón, Joel Chappell…·Vincent Pasque

This study investigates the dynamics of X-chromosome reactivation during mouse iPSC reprogramming, revealing hierarchical gene activation patterns and the role of chromatin regulators.

57 citations

mousebulk RNA-seq

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