Phillip A. Dumesic

The paper identifies cell-autonomous and systemic circadian gene expression programs in adipocytes using RNA sequencing and motif analysis, revealing distinct regulatory programs linked to metabolic processes.

This study shows that cardiomyocyte PGC-1α is essential for cardiac adaptation to endurance exercise by suppressing GDF15 and preventing cardiac atrophy in mice.

This study identifies UCP4b as a cold-inducible gene in Drosophila that protects against cold and obesity, regulated by calcium signaling and counteracted by BMP signaling via MAD.

The paper shows that ATP hydrolysis by the SNF2 domain of Dnmt5 is coupled to DNA methylation, enhancing substrate specificity through base-flipping mechanisms.

The paper shows that DNA methylation persists in Cryptococcus neoformans despite the loss of a de novo methyltransferase, with methylation patterns maintained through replication and natural selection.