Zbyněk Kozmík

This study shows that pax6 is critical for dorsoventral patterning and nerve cord development in Platynereis, supporting a conserved role in bilaterian nervous system evolution.

The paper integrates single-cell, spatial, and clonal data to study cranial placode development and evolution, revealing continuous transcriptional landscapes and shared progenitors between placodes.

This study investigates Pax6's role in lens development using a Foxe3-Cre driver, showing its necessity for maintaining epithelial identity and coordinating fiber cell differentiation.

The paper identifies vertebrate head-related cell populations in amphioxus, a close relative of the chordate ancestor, through single-cell transcriptomics and functional analysis.

This study investigates the role of Pax6 in amphioxus CNS development, finding altered gene expression in mutants and supporting a conserved role in brain regionalization.

The paper identifies conserved notochord-specific enhancers of Brachyury/T/TBXT in vertebrates and shows their role in notochord expression and development.

This study shows that Snf2h is essential for retinal progenitor cell proliferation and photoreceptor maintenance, leading to retinal dysfunction when Snf2h is deleted.

This study investigates the role of Pax6 in corneal limbal epithelial cells and maturing epithelial cell adhesion through conditional depletion in different ocular domains.

This study identifies the MEIS-WNT5A axis as critical for the development and morphology of the fourth ventricle choroid plexus.

This paper identifies new retinal ganglion cell types and brain nuclei expressing Brn3c using a novel Cre allele, revealing expanded RGC diversity and novel connectivity patterns.

The paper identifies a conserved regulatory program driving lateral plate mesoderm emergence across chordates using zebrafish and comparative analysis.