Author
University Hospital Carl Gustav CarusORCID 0000-0002-5916-3029Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Jan-Malte Kleid, Michael Damrat, Milita Darguzyte…·Renata Stripecke
This study develops next-generation CD30CAR-T cells using CRISPR/Cas9 for multiplex editing, showing high potency but risks of translocations with combined knockouts.
Vida Kufrin, Annika Seiler, Silke Brilloff…·Alexander Arthur Wurm
This study identifies KAT2A as a therapeutic target in a subset of well-differentiated, microsatellite-stable colorectal cancers by showing its dependency and functional consequences.
Cornelius Pauli, Michael Kienhöfer, Maximilian Felix Blank…·Michaela Frye
The paper identifies essential RNA modifications in cancer using CRISPR screens and finds that mitochondrial metabolic plasticity influences drug resistance through specific RNA modifications.
Wei‐Yu Lin, Sarah Elizabeth Fordham, Eric A. Hungate…·James M. Allan
This study identifies two genome-wide significant susceptibility loci for acute myeloid leukemia through a meta-analysis of GWAS data.
Ceren Güneş, Maciej Paszkowski‐Rogacz, Susann Rahmig…·Frank Buchholz
The paper uses RNAi screens in isogenic human stem cells to identify SMARCA4 as a differential regulator of stemness and differentiation in hematopoietic and neural stem cells.