Isabel Fabregat

This study shows ZEB1 in cancer-associated fibroblasts regulates BCL2 to promote chemoresistance in cholangiocarcinoma, suggesting BCL2 inhibitors could enhance gemcitabine and cisplatin efficacy.

This study identifies ceruloplasmin deficiency in mutant astrocytes as a driver of iron toxicity and neurodegeneration in a Parkinson's tri-culture model.

This study shows that inhibiting EGFR in hepatocytes reduces liver fibrosis by altering immune cell populations and molecular mechanisms involved in inflammation and fibrogenesis.