Achinta Sannigrahi

This study shows that host sphingomyelin and cholesterol act as a lipid chaperone to facilitate the conformational changes of the bacterial toxin Cytolysin A, enabling pore formation.

The paper maps the human ER subdomain proteome, identifies CLMN as an ER-actin tether at focal adhesions, and shows it promotes cell migration by regulating actin dynamics and calcium signaling.

This paper identifies KMP-11 as a key Leishmania protein that mediates host cell invasion via cholesterol transport and membrane phase transition.