Yupu Xu

The paper introduces GPD, a framework using gene co-expression programs to create an organism-wide cell atlas, revealing disease-related gene programs across tissues.

SpacGPA annotates spatial transcriptomes by identifying interpretable gene programs without single-cell data or segmentation.

SingleCellGGM identifies gene expression programs from single-cell transcriptomes and enables cross-study cell-type label transfer.

The paper develops a CRISPR/Cas9 system for Arabidopsis using the NUC1 promoter, achieving high editing efficiency and stable inheritance in the T2 generation.

The paper develops a gene expression predictor for Arabidopsis that uses TF activities to accurately predict transcriptomes and infer TF regulators for specific biological processes.