Thomas Booth

The paper reports a case of human infection with an ape-like Plasmodium vivax parasite, identified through whole-genome sequencing, suggesting zoonotic transmission from wild gorillas and chimpanzees.

The paper describes a new secondary chromosome, EEC1, in the Embleya genus, which is distinct from other secondary replicons and plays a key role in the genus' metabolism and evolution.

The paper develops Telomore to recover missing telomeres in Streptomycetaceae genomes, increasing detection from 0% to 37% and identifying a new telomere-related protein family.

This paper introduces ActinoMation, a tool for automating Streptomyces conjugation, achieving varying conjugation efficiencies across strains and plasmids.

getphylo automatically generates multi-locus phylogenetic trees from GenBank files, offering faster and more flexible analysis than existing tools.

The paper provides over 1,000 high-quality Actinomycetia genomes, revealing genomic structures and biosynthetic gene cluster organization with ecological and biotechnological implications.

The paper analyzes 2,371 Streptomyces genomes to refine biosynthetic gene cluster (BGC) diversity using MASH-clusters and reveals conserved genomic structures suggesting vertical inheritance.

This study identifies and characterizes the biosynthetic pathway for azodyrecin, an azoxy compound produced by Streptomyces mirabilis P8-A2, revealing key enzymes and gene cluster distribution across Streptomyces species.

CAGECAT enables rapid homology searches and visualization of gene clusters across genomes, aiding in the discovery of novel metabolites through comparative analysis.

cblaster identifies and visualizes homologous gene clusters across local and remote databases, enhancing comparative genomics analysis.