Kathleen R. Nicholson

This study examines the structure and function of Neisseria gonorrhoeae TfpC, revealing its dynamic two-domain architecture essential for type IV pilus function.

This study shows that loss of PDIM and PGL lipids in M. marinum reduces specific ESX-1 substrate secretion, impacting pathogenesis.

This study identifies EspN as a critical transcription factor regulating the ESX-1 system in M. marinum, which is essential for macrophage infection and disease burden, but its activity is masked by EspM under laboratory conditions.