Bingqing Xia

This study introduces a nanopore-based method for glycan sequencing that reconstructs full glycan structures from fragments, overcoming limitations of existing approaches.

This study identifies TMEM41B as an ER Ca2+ release channel that maintains T cell metabolic quiescence and responsiveness by regulating signaling pathways and receptor expression.

This paper demonstrates a glycan sequencing method using glycosidase-assisted nanopore sensing, achieving over 90% accuracy in identifying monosaccharide sequences.

This paper demonstrates a method for glycan sequencing using nanopores by conjugating glycans to helicase-controlled DNA, achieving reads of up to eleven glycans and enabling controlled translocation and signal detection.

The paper identifies that the human microbiota contributes to SARS-CoV-2 mutations by replicating bacterial mRNAs with advantageous mutations, leading to chimeric RNAs and altered viral properties.

This paper designs an engineered nanopore to distinguish isomeric glycans with high sensitivity and achieves over 90% separation accuracy without machine learning.